BNC682906
CD72 (B Cell Marker)(BU40), CF568 conjugate, 0.1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNC682906
- Zusätzliche Namen:
- B cell differentiation antigen CD72; CD72b; CD72c; Ly-19; Ly-32; Ly-m19; LYB2; Lymphocyte antigen 32
- Anwendung:
- IHC-P
- Konzentration:
- 0.1 mg/ml
- Molekulargewicht:
- 45 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Bovine, Human, Mouse
- Buffer:
- 0.05% sodium azide|PBS, 0.1% BSA, 0.05% azide
- Immunogen:
- HF B1 plasmacytoid cell line.
- Formulierung:
- PBS, 0.1% BSA, 0.05% azide
- Klon:
- BU40
- Uniprot:
- P21854
- Synonyme:
- B-cell differentiation antigen CD72;CD72 antigen;CD72b;crooked neck pre-mRNA splicing factor-like 1 pseudogene;lyb-2;LYB2
- Weitere Details:
- The C-type lectin superfamily member CD72 is a cell surface negative regulator of B cell activation from the pro-B through the mature B cell stage. CD72 serves as a receptor for CD5. The human CD72 gene encodes a transmembrane glycoprotein that contains an immunoreceptor tyrosine-based inhibition motif (ITIM). Upon tyrosine phosphorylation, the CD72 ITIM recruits SH2-containing phosphatases such as SHP-1, resulting in downregulation of cell activation. CD72-/- mice contain hyperproliferative B cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient