BNC472247
NME1 / nm23-H1 / NDPK-A (Suppressor of Metastasis)(CPTC-NME1-2), CF647 conjugate, 0.1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNC472247
- Zusätzliche Namen:
- AWD; GAAD; Granzyme A activated DNase; Metastasis inhibition factor NM23; NB; NBS; NDP kinase A; NM23 long variant; included; NM23H1B; NME/NM23 nucleoside diphosphate kinase 1; NME1-NME2 spliced read-through transcript; included; Non-metastatic protein 23; homolog 1; Nucleoside diphosphate kinase A; Tumor metastatic process-associated protein
- Anwendung:
- WB
- Konzentration:
- 0.1 mg/ml
- Molekulargewicht:
- 23 kda
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Mouse
- Reaktivitäten:
- Bovine, Human, Mouse
- Buffer:
- 0.05% sodium azide|PBS, 0.1% BSA, 0.05% azide
- Immunogen:
- Recombinant full-length human NME1 protein
- Formulierung:
- PBS, 0.1% BSA, 0.05% azide
- Klon:
- CPTC-NME1-2
- Uniprot:
- P15531
- Synonyme:
- AWD;epididymis secretory sperm binding protein;GAAD;granzyme A-activated DNase;metastasis inhibition factor nm23;NB;NBS;NDKA;NDP kinase A;NDPK-A;NDPKA;NM23;NM23-H1;non-metastatic cells 1, protein (NM23A) expressed in;nucleoside diphosphate kinase A;tumor metastatic process-associated protein
- Weitere Details:
- The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP-K). In humans, NDP kinase A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human C-Myc promotor. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient