BNC472005
CD40, Mouse(FGK45.5), CF647 conjugate, 0.1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNC472005
- Zusätzliche Namen:
- B cell surface antigen CD40; CD40 type II isoform; p50; Bp50; CD40L receptor; CDW40; TRAP; IMD3; IGM; Tnfrsf5; HIGM1; GP39; T-BAM
- Anwendung:
- Flow Cytometry, FuncS
- Konzentration:
- 0.1 mg/ml
- Molekulargewicht:
- 48 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Rat
- Reaktivitäten:
- Bovine, Mouse, Rat
- Buffer:
- 0.05% sodium azide|PBS, 0.1% BSA, 0.05% azide
- Immunogen:
- Purified recombinant Mouse CD40 fusion protein
- Formulierung:
- PBS, 0.1% BSA, 0.05% azide
- Klon:
- FGK45.5
- Uniprot:
- P27512
- Synonyme:
- AI326936;B-cell surface antigen CD40;Bp5;Bp50;CD40L receptor;GP39;HIGM1;IGM;IMD3;p5;p50;T-BAM;T-cell differentiation antigen;Tnfr;Tnfrsf5;TRAP;tumor necrosis factor receptor superfamily member 5
- Weitere Details:
- Upon binding to its ligand CD154, CD40 acts as a costimulatory molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation, differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4. 5 can be used for blocking of CD40/CD154 interaction and forin vitroandin vivoactivation of CD40 expressing APCs. This MAb is shown to indirectly activate natural killer (NK) cells, producing significant antitumor and anti-metastatic effects. Effective in boosting immune responses against infectious agents and can potentially be used to treat chronic autoimmune inflammatory processes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient