CD4 (T-Helper/Inducer Cell Marker)(CD4/3027), CF405S conjugate, 0.1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:: BNC043027
Zusätzliche Namen:: L3T4; Leu3; Ly-4; Lymphocyte antigen CD4; p55; T cell antigen T4/LEU3; T cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4
Konzentration:: 0.1 mg/ml
Molekulargewicht:: 55 kDa
Quelle:: Animal
Lagerbedingungen:: 2-8[o]C, RT
Hersteller:: Biotium
Host:: Mouse
Reaktivitäten:: Human
Buffer:: 0.05% sodium azide|PBS, 0.1% BSA, 0.05% azide
Immunogen:: Recombinant human CD4 protein extracellular domain fragment (around aa 245-392) (exact sequence is proprietary)
Formulierung:: PBS, 0.1% BSA, 0.05% azide
Klon:: CD4/3027
Uniprot:: P01730
Synonyme:: CD4 antigen (p55);CD4 receptor;CD4mut;IMD79;OKT4D;T-cell surface antigen T4/Leu-3;T-cell surface glycoprotein CD4
Weitere Details:: The immunogen for this Mab is derived from the extracellular domain of CD4, a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. The majority of peripheral T-cell lymphomas are derived from the T-helper/regulatory cell subset so that most mature T-cell neoplasms are CD4 /CD8-. Anti-CD4 is used in the immunohistochemical staining of lymphoproliferative disorders to evaluate tumors with CD4 aberrant expression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Versandbedingungen:: Ambient