EGFR(31G7), CF405S conjugate, 0.1mg/mL

Eine Lieferung in diese Region ist nicht möglich.

SKU:: BNC041194
Zusätzliche Namen:: Erbb1; ERBB1; Errp; HER1; mENA; PIG61; Proto-oncogene c-ErbB-1; Receptor Tyrosine Protein Kinase; ErbB1; Urogastrone; wa2; Wa5
Anwendung:: IHC-P
Konzentration:: 0.1 mg/ml
Molekulargewicht:: ~170 kDa (wild type) and ~145 kDa (vIII variant)
Quelle:: Animal
Lagerbedingungen:: 2-8[o]C, RT
Hersteller:: Biotium
Host:: Mouse
Reaktivitäten:: Bovine, Human, Mouse
Buffer:: 0.05% sodium azide|PBS, 0.1% BSA, 0.05% azide
Immunogen:: Human EGFR purified from A431 cells
Formulierung:: PBS, 0.1% BSA, 0.05% azide
Klon:: 31G7
Uniprot:: P00533
Synonyme:: avian erythroblastic leukemia viral (v-erb-b) oncogene homolog;cell growth inhibiting protein 40;cell proliferation-inducing protein 61;epidermal growth factor receptor;epidermal growth factor receptor tyrosine kinase domain;erb-b2 receptor tyrosine kinase 1;ERBB;ERBB1;ERRP;HER1;mENA;NISBD2;PIG61;proto-oncogene c-ErbB-1;receptor tyrosine-protein kinase erbB-1
Weitere Details:: This MAb recognizes a protein of 170 kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Versandbedingungen:: Ambient