BNC040308
Laminin(A5), CF405S conjugate, 0.1mg/mL
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- BNC040308
- Zusätzliche Namen:
- LAMB2; LAMC1; Laminin B2 chain; Laminin gamma 1; Laminin gamma 1 chain
- Konzentration:
- 0.1 mg/ml
- Molekulargewicht:
- 210 kDa
- Quelle:
- Animal
- Lagerbedingungen:
- 2-8[o]C, RT
- Hersteller:
- Biotium
- Host:
- Rat
- Reaktivitäten:
- Bovine, Human, Mouse, Rat
- Buffer:
- 0.05% sodium azide|PBS, 0.1% BSA, 0.05% azide
- Immunogen:
- Murine EHS laminin preparation
- Formulierung:
- PBS, 0.1% BSA, 0.05% azide
- Klon:
- A5
- Uniprot:
- P11047, Q5VYE7, Q6NVY8
- Synonyme:
- LAMB2;laminin B2 chain;laminin subunit gamma-1;Laminin-1 subunit gamma;laminin-10 subunit gamma;laminin-11 subunit gamma;laminin-2 subunit gamma;laminin-3 subunit gamma;laminin-4 subunit gamma;laminin-6 subunit gamma;laminin-7 subunit gamma;laminin-8 subunit gamma;laminin-9 subunit gamma;laminin, gamma 1 (formerly LAMB2);S-LAM gamma;S-laminin subunit gamma
- Weitere Details:
- Laminins are large hetero-trimeric, non-collagenous glycoproteins composed of A Alpha, B Beta, and G Gamma chains. This MAb reacts with laminin B2/1 chain of ~210 kDa and does not cross-react with other basement membrane components or fibronectin. Its specificity was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs. Epithelial sheets in vivo are separated from the mesenchymal elements of the stroma by a thin layer of a specialized type of extracellular matrix termed the basement membrane (BM). This structure consists of individual components, some of which are ubiquitous in BMs and some are not. The ubiquitous ones comprise laminin (LN), entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms. This MAb stains uniformly all human and murine basement membranes.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Versandbedingungen:
- Ambient