Polyclonal Antibody to IDH1

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£319.00

SKU:: 11-7527
Zusätzliche Namen:: IDH1||PICD
Aufreinigung:: Protein A Chromatography
Hersteller:: Abeomics Inc.
Host:: Rabbit
Reaktivitäten:: Human
Uniprot:: O75874
Gendetails:: IDH1
Weitere Details:: Isocitrate dehydrogenase 1 (IDH1) is a dimeric cytosolic NADP-dependent dehydrogenase that catalyzes decarboxylation of isocitrate into alpha-ketoglutarate. It belongs to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). It serves a significant role in cytoplasmic NADPH production. It is found in the cytoplasm and peroxisomes. IDH1 is of great importance in cell metabolism and energy conversion. Mutations in IDH1 are found in a somatic mosaic fashion in patients with multiple enchondromas.