Polyclonal Antibody to 14-3-3 Zeta

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£319.00

SKU:: 11-1017
Zusätzliche Namen:: YWHAZ
Aufreinigung:: Protein A Chromatography
Hersteller:: Abeomics Inc.
Host:: Rabbit
Reaktivitäten:: Human
Uniprot:: P63104
Gendetails:: YWHAZ
Weitere Details:: 14-3-3zeta is a central cellular hub protein regulating multiple signaling pathways involved in cancer development, progression and therapeutic resistance. It is linked to endoplasmic reticulum (ER) function in neurons, with reduced levels provoking ER stress and increasing vulnerability to excitotoxic injury. It is up-regulated in malignancy, which suggests its potential as a putative drug target for the treatment of colorectal cancer and tumorgenesis in pancreas,EOC (epithelial ovarian cancer).