Monoclonal Antibody to FSH Receptor (Clone: ABM5D29)

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£319.00

SKU:: 10-7600
Zusätzliche Namen:: Follicle-stimulating hormone receptor, FSH-R, Follitropin receptor
Aufreinigung:: Protein G Chromatography
Hersteller:: Abeomics Inc.
Host:: Mouse
Reaktivitäten:: Human
Klon:: ABM5D29
Uniprot:: P23945
Gendetails:: FSHR
Weitere Details:: FSH receptor is a member of the G protein coupled receptor family consisting of 9 introns and 10 exons and a promoter region and is located on chromosome 2p21. FSH receptor was shown to be expressed selectively on the luminal surface of tumor blood vessels. A general characteristic of the blood vessels that express the endothelial FSH receptor is that they are located at the periphery of the tumors. Many studies showed that FSH receptor polymorphisms at positions 307 and 680 may be even more relevant for clinical practice for the reasons of regulating the ovarian reaction to hormone, controlling ovarian hyperstimulation, changing the menstrual cycle, and causing POF (Premature Ovarian Failure) and PCOS (Polycystic Ovary Syndrome).