Monoclonal Antibody to MLH1 (Clone: ABM4D74)

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£319.00

SKU:: 10-7573
Zusätzliche Namen:: MLH1||COCA2
Aufreinigung:: Protein G Chromatography
Hersteller:: Abeomics Inc.
Host:: Mouse
Reaktivitäten:: Human
Klon:: ABM4D74
Uniprot:: P40692
Gendetails:: MLH1
Weitere Details:: MutL homolog 1 (MLH1) is a member of mismatch repair genes (MMR) that plays a crucial role in correcting replication errors, cell cycle arrest, apoptosis and oxidative stress. MLH1 is a human homolog of the E.coli DNA mismatch repair gene. It mediates protein-protein interactions during mismatch recognition, strand discrimination, and strand removal. Diseases associated with MLH1 include colorectal cancer, hereditary nonpolyposis, type 2 and lynch syndrome.