Monoclonal Antibody to Napsin A (Clone: ABM4H60)

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£319.00

SKU:: 10-7568
Zusätzliche Namen:: NAPSA||NAP1||NAPA
Aufreinigung:: Protein G Chromatography
Hersteller:: Abeomics Inc.
Host:: Mouse
Reaktivitäten:: Human
Klon:: ABM4H60
Uniprot:: O96009
Gendetails:: NAPSA
Weitere Details:: Napsin A, a human aspartic proteinase is found primarily in type II pneumocytes and alveolar macrophages and predominantly expressed in lung and kidney. It is a reliable marker for pulmonary adenocarcinoma and is expressed in a subset of ovarian clear cell carcinomas (O-CCCs), endometrial (EM) CCCs, and endometrioid carcinomas (EC). It is also useful in evaluating SH (Sclerosing hemangiomas) (23194051). Napsin A acts as an anti-apoptotic protein that promotes resistance to cisplatin by degradation of the tumor suppressor p53, which is regulator of the cell cycle and co-works with cyclin kinase inhibitors as p21 and p27.