Monoclonal Antibody to SOX11 (Clone: ABM45D9)

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£319.00

SKU:: 10-7567
Zusätzliche Namen:: SOX11
Aufreinigung:: Protein G Chromatography
Hersteller:: Abeomics Inc.
Host:: Mouse
Reaktivitäten:: Human, Mouse
Klon:: ABM45D9
Uniprot:: P35716
Gendetails:: SOX11
Weitere Details:: SOX11 (Sex determining region Y-box 11), located on chromosome 2p25, belong to the family of genes SOXC. It is a transcript factor involved in the embryonic neurogenesis and tissue remodeling, also participating in the control of cell proliferation. It is involved in gastrulation and in malignant diseases. It is expressed in foetal and neoplastic brain tissue, including gliomas (23619925). SOX11 is overexpressed in several solid tumors and in the vast majority of aggressive mantle cell lymphomas (MCLs). Diseases associated with SOX11 include mental retardation, autosomal dominant, 27 and coffin-siris syndrome.