Monoclonal Antibody to Mouse EBI3 (Clone: ABM2C40)

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£319.00

SKU:: 10-4021
Zusätzliche Namen:: Ebi3||Il27b
Aufreinigung:: Protein G Chromatography
Hersteller:: Abeomics Inc.
Host:: Rat
Reaktivitäten:: Mouse
Klon:: ABM2C40
Uniprot:: O35228
Gendetails:: Ebi3
Weitere Details:: Epstein-Barr Virus Induced Gene 3 (EBI3) is an immune regulator that has been associated with the pathogenesis of inflammatory bowel disease. EBI3, as part of the immunosuppressive IL-35 cytokine, plays an important role in the regulation of intestinal immune responses by controlling overwhelming T-cell activation. EBI3 deficiency does not lead to changes in intestinal pathology in trinitrobenzene sulfonic acid colitis, but is protective in oxazolone-induced colitis.