Monoclonal Antibody to TLR8/CD288 (Clone: ABM15F6)

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£319.00

SKU:: 10-3005
Zusätzliche Namen:: TLR8||UNQ249/PRO286
Aufreinigung:: Protein G Chromatography
Hersteller:: Abeomics Inc.
Host:: Mouse
Reaktivitäten:: Human
Klon:: ABM15F6
Uniprot:: Q9NR97
Gendetails:: TLR8
Weitere Details:: Toll like receptor 8, also known as CD288, is a member of TLR family. It plays an important role in sensing phagocytosed pathogen. TLR8 recognizes ssRNA and recruits MyD88 and leads to the activation of transcription factor NF-kappa B. TLR8 TLR8 has two splice variants, viz., TLR8v1 and TLR8v2 and one missense variant, termed G or A1G allele of TLR8. TLR8v1 has additional 19 amino acids in the N-terminus. It is predominantly expressed in lung and peripheral blood leukocytes.