Recombinant Human PD-1 rabbit monoclonal Antibody (Clone: ABMRR01)

Größe

£319.00

SKU:: 10-2001
Zusätzliche Namen:: PDCD1, PD1, CD279
Aufreinigung:: Protein A Chromatography
Hersteller:: Abeomics Inc.
Reaktivitäten:: Human
Klon:: ABMRR01
Uniprot:: Q15116
Gendetails:: PDCD1
Weitere Details:: PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.