Human CEACAM5 Monoclonal Antibody

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£355.00

SKU:: YR0166
Zusätzliche Namen:: CD66e, CEA
Anwendung:: ELISA, FuncS, Neutralisation
Molekulargewicht:: 150 kDa
Reinheit:: >95%
Lagerbedingungen:: 2-8[o]C Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Immunogen:: Human CEACAM5
Formulierung:: Purified from cell culture supernatant in an animal-free facility
Uniprot:: P06731
Synonyme:: Carcinoembryonic antigen;carcinoembryonic antigen related cell adhesion molecule 5;carcinoembryonic antigen-related cell adhesion molecule 5;CD66e;CEA;meconium antigen 100
Weitere Details:: What is tusamitamab biosimilar research grade? Tusamitamab is a humanized IgG1-kappa monoclonal antibody targeting carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) which is overexpressed in tumors including non-small cell lung cancer (NSCLC) and pancreatic ductal adenocarcinoma (PDAC), and is an attractive target for therapies based on CAR-T cell or/and ADCs. Tusamitamab ravtansine (SAR408701) is an antibody-drug conjugate (ADC) combining a humanized monoclonal antibody and a potent cytotoxic maytansinoid derivative (DM4) inhibiting microtubule assembly. Tusamitamab biosimilar uses the same protein sequences as the therapeutic antibody tusamitamab.