YR0137
Human Claudin 18.2 Monoclonal Antibody
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£355.00
- SKU:
- YR0137
- Zusätzliche Namen:
- CLDN18|SFTA5|SFTPJ
- Anwendung:
- ELISA, FuncS, Neutralisation
- Molekulargewicht:
- 150 kDa
- Reinheit:
- >95%
- Lagerbedingungen:
- 2-8[o]C Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Immunogen:
- Human Claudin 18
- Formulierung:
- Purified from cell culture supernatant in an animal-free facility
- Uniprot:
- P56856-2
- Synonyme:
- claudin-18;SFTA5;SFTPJ;surfactant associated 5;surfactant associated protein J;surfactant, pulmonary associated protein J
- Weitere Details:
- Zolbetuximab is a humanized monoclonal antibody directed against the human protein Claudin 18.2 (the isoform 2 of Claudin), and potentially used for the treatment of gastrointestinal adenocarcinomas and pancreatic tumors. Zolbetuximab is an Fc-engineered, humanized, monoclonal antibody (IgG1K Kappa isotype). Zolbetuximab biosimilar uses the same protein sequences as the potential therapeutic antibody zolbetuximab .Claudin-18 in humans is a protein encoded by the CLDN18 gene. The CLDN18 protein belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. Isoform 2 (Claudin 18.2) is abundant in gastric tumors.
- Versandbedingungen:
- Blue Ice