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YR0123

Human CD79B Monoclonal Antibody

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£355.00

SKU:
YR0123
Zusätzliche Namen:
AGM6|B29|IGB|Igbeta
Anwendung:
ELISA, FuncS, Neutralisation
Molekulargewicht:
150 kDa
Reinheit:
>95%
Lagerbedingungen:
2-8[o]C Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
Hersteller:
Abclonal
Immunogen:
Human CD79B
Formulierung:
Purified from cell culture supernatant in an animal-free facility
Uniprot:
P40259
Synonyme:
AGM6;B-cell antigen receptor complex-associated protein beta chain;B-cell-specific glycoprotein B29;B29;CD79b antigen (immunoglobulin-associated beta);CD79b molecule, immunoglobulin-associated beta;Ig-beta;IGB;immunoglobulin-associated B29 protein
Weitere Details:
Polatuzumab is a humanized IgG1-kappa monoclonal antibody against the human CD79B protein, which is ubiquitously expressed on the surface of malignant B cells. Polatuzumab vedotin is used to treat diffuse large B-cell lymphoma (DLBCL) after at least two other cancer treatments did not work or have stopped working. It is given in combination with bendamustine (Bendeka, Treanda) and a medicine that contains rituximab (Rituxan). Polatuzumab vedotin works by attaching to CD79b and releasing a toxic substance that kills the cancer cells. Polatuzumab biosimilar uses the same protein sequences as the therapeutic antibody polatuzumab.
Versandbedingungen:
Blue Ice