Human CD11a Monoclonal Antibody

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£355.00

SKU:: YR0111
Zusätzliche Namen:: CD11A|LFA-1|LFA1A
Anwendung:: ELISA, FuncS, Neutralisation
Molekulargewicht:: 150 kDa
Reinheit:: >95%
Lagerbedingungen:: 2-8[o]C Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Immunogen:: Human CD11a
Formulierung:: Purified from cell culture supernatant in an animal-free facility
Uniprot:: P20701
Synonyme:: antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide;CD11 antigen-like family member A;CD11A;integrin alpha-L;integrin gene promoter;integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide);leukocyte adhesion glycoprotein LFA-1 alpha chain;leukocyte function-associated molecule 1 alpha chain;LFA-1;LFA-1 alpha;LFA-1A;LFA1A;lymphocyte function-associated antigen 1, alpha polypeptide
Weitere Details:: Efalizumab is a monoclonal anti-CD11a antibody used to treat moderate to severe plaque psoriasis.Humanized IgG1 kappa isotype monoclonal antibody that binds to human CD11a. Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin.Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes. As a result efalizumab decreases cell surface expression of CD11a.