YR0003
Human IL-6R Monoclonal Antibody
Größe
£355.00
- SKU:
- YR0003
- Zusätzliche Namen:
- CD126|gp80|HIES5|IL-1Ra|IL-6R|IL-6R-1|IL-6RA|IL6Q|IL6QTL|IL6RA|IL6RQ
- Anwendung:
- ELISA, FuncS, Neutralisation
- Molekulargewicht:
- 150 kDa
- Reinheit:
- >95%
- Lagerbedingungen:
- 2-8[o]C Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Immunogen:
- Human IL-6R
- Formulierung:
- Purified from cell culture supernatant in an animal-free facility
- Uniprot:
- P08887
- Synonyme:
- CD126;CD126 antigen;gp80;HIES5;IL-1Ra;IL-6 receptor subunit alpha;IL-6R;IL-6R 1;IL-6R-1;IL-6RA;IL6Q;IL6QTL;IL6RA;IL6RQ;interleukin-6 receptor subunit alpha;membrane glycoprotein 80
- Weitere Details:
- What is tocilizumab biosimilar research grade? Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. Interleukin 6 (IL-6) is a pro-inflammatory cytokine produced by cells including T-cells, B-cells, lymphocytes, monocytes, fibroblasts. IL-6 rapidly induces C-reactive protein, serum amyloid A, fibrinogen, haptoglobin, and A Alpha-1-antichymotrypsin while inhibiting production of fibronectin, albumin, and transferrin. IL-6 also induces antibody production, induces cytotoxic T-cell differentiation, and inhibits regulatory T-cell differentiation. Tocilizumab binds soluble and membrane bound IL-6 receptors, preventing IL-6 mediated inflammation.
- Versandbedingungen:
- Blue Ice