Recombinant Human Annexin A1/ANXA1 Protein

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SKU:: RP03265
Zusätzliche Namen:: Annexin A1|Annexin I|Annexin-1|ANX1|ANXA1|Calpactin II|Calpactin-2|Chromobindin-9|Lipocortin I|LPC1|p35
Molekulargewicht:: 35-40 kDa
Reinheit:: ≥95%
Lagerbedingungen:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Immunogen:: Met1-Asn346
Formulierung:: Recombinant Human ANXA1 Protein is produced by E.coli expression system. The target protein is expressed with sequence (Met1-Asn346) of human ANXA1 (Accession #P04083) fused with His tag at the C-terminus.
Spezies:: Human
Sequenz:: MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN
Uniprot:: P04083
Synonyme:: annexin A1;Annexin I;annexin I (lipocortin I);annexin-1;ANX1;calpactin II;calpactin-2;chromobindin-9;epididymis secretory sperm binding protein;Lipocortin I;LPC1;p35;phospholipase A2 inhibitory protein
Weitere Details:: Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance.

Versandbedingungen:: Blue Ice