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RP03182

Recombinant Mouse IGFBP-2 Protein

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£145.00

SKU:
RP03182
Zusätzliche Namen:
IBP2, IGF-BP53,IGFBP2,IGF-BP53
Molekulargewicht:
35-40 kDa
Reinheit:
≥95%
Lagerbedingungen:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Hersteller:
Abclonal
Immunogen:
Met1-Gln305
Formulierung:
Recombinant Mouse IGFBP-2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Gln305) of mouse IGFBP-2 (Accession #P47877) fused with an initial Met at the N-terminus and a 6xHis tag at the C-terminus.
Spezies:
Mouse
Sequenz:
MLPRLGGPALPLLLPSLLLLLLLGAGGCGPGVRAEVLFRCPPCTPERLAACGPPPDAPCAELVREPGCGCCSVCARQEGEACGVYIPRCAQTLRCYPNPGSELPLKALVTGAGTCEKRRVGTTPQQVADSDDDHSEGGLVENHVDGTMNMLGGGSSAGRKPLKSGMKELAVFREKVNEQHRQMGKGAKHLSLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDDRGPLEHLYSLHIPNCDKHGRYNLKQCKMSLNGQRGECWCVNPNTGKPIQGAPTIRGDPECHLFYNEQQETGGAHAQSVQ
Uniprot:
P47877
Synonyme:
AI255832;IBP-2;IGF-binding protein 2;IGFBP;Igfbp-2;insulin-like growth factor-binding protein 2;mIGFBP-2
Weitere Details:
IGFBP-2, also known as IGFBP2, is a insulin-like growth factor-binding protein (IGFBP). IGFBPs have a high affinity for IGFs. Some members of the IGFBP family have been consistently shown to inhibit IGF actions by preventing them from gaining access to the IGF receptors, while others potentiate IGF actions by facilitating the ligand-receptor interaction. IGFBP2 is overexpressed in many malignancies and is often correlated with an increasingly malignant status of the tumor, pointing to a potential involvement of IGFBP2 in tumorigenesis.
Versandbedingungen:
Blue Ice