Recombinant Mouse PDGF-AA Protein

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£574.00

SKU:: RP03145
Zusätzliche Namen:: PDGF-A|PDGF1|PDGFA
Molekulargewicht:: 20&26 KDa
Reinheit:: ≥95%
Lagerbedingungen:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Immunogen:: Ser87-Arg196
Formulierung:: Recombinant Mouse PDGF-AA Protein is produced by Pichia expression system. The target protein is expressed with sequence (Ser87-Arg196) of Mouse PDGF-AA (Accession #NP_032834.1) fused with a 6xHis tag at the N-terminus.
Spezies:: Mouse
Sequenz:: SIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATSNLNPDHREEETGRR
Uniprot:: P20033
Synonyme:: PDGF A-chain;PDGF subunit A;PDGF-1;Platelet-derived growth factor A chain;platelet-derived growth factor A-chain;platelet-derived growth factor alpha polypeptide;platelet-derived growth factor subunit A
Weitere Details:: Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site.