RP02953
Recombinant Human LRG1 Protein
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£145.00
- SKU:
- RP02953
- Zusätzliche Namen:
- LRG1, LRG, Leucine-rich alpha-2-glycoprotein, LRG
- Molekulargewicht:
- 45-60 kDa
- Reinheit:
- ≥95%
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Immunogen:
- Vla36-Gln347
- Formulierung:
- Recombinant Human LRG1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Vla36-Gln347) of Human LRG1 fused with His tag at the C-terminus.
- Spezies:
- Human
- Uniprot:
- P02750
- Synonyme:
- 1300008B03Rik;2310031E04Rik;HMFT1766;leucine rich alpha 2 glycoprotein;leucine-rich alpha-2-glycoprotein;LRG
- Weitere Details:
- LRG1 is a Protein Coding gene. LRG1 belongs to the leucine-rich repeat (LRR) family. Members of this family are involved in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation. It contains 4 LIM zinc-binding domains and 1 Rho-GAP domain. LRG1 is involved in promoting neovascularization (new blood vessel growth) by causing a switch in transforming growth factor-beta (TGFbeta) signaling in endothelial cells. LRG1 binds to the accessory receptor endoglin and promotes signaling via the ALK1-Smad1/5/8 pathway. It may be a potential therapeutic target for the treatment of diseases where there is aberrant neovascularization. Diseases associated with LRG1 include Appendicitis and Normal Pressure Hydrocephalus.
- Versandbedingungen:
- Blue Ice