Recombinant Human Calumenin/CALU Protein

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£145.00

SKU:: RP02945
Zusätzliche Namen:: CALU, calumenin,Calumenin,calumenin
Molekulargewicht:: 40-55 kDa
Reinheit:: ≥ 80 %
Lagerbedingungen:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Immunogen:: Lys20-Phe315
Formulierung:: Recombinant Human Calumenin/CALU Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Lys20-Phe315) of Human Calumenin/CALU (Accession #NP_001210.1) fused with a 6xHis tag at the C-terminus.
Spezies:: Human
Sequenz:: KPTEKKDRVHHEPQLSDKVHNDAQSFDYDHDAFLGAEEAKTFDQLTPEESKERLGKIVSKIDGDKDGFVTVDELKDWIKFAQKRWIYEDVERQWKGHDLNEDGLVSWEEYKNATYGYVLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF
Uniprot:: O43852
Synonyme:: calumenin;Crocalbin;crocalbin-like protein;IEF SSP 9302;multiple EF-hand protein
Weitere Details:: Calumenin is a secreted calcium-binding protein that belongs to the CREC family. Calumenin contains six EF-hand domains and is expressed at high levels in the heart, placenta and skeletal muscle. Human Calumenin is synthesized as a 315 amino acid precursor that contains a 19 amino acid signal sequence, and a 296 amino acid mature chain. Calumenin localizes to the endoplasmic reticulum (ER) and sarcoplasmic reticulum (SR) of mammalian tissues which plays a role in ER functions as protein folding and sorting. Calumenin is involved in the regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. It seems to inhibit G Gamma-carboxylase GGCX.

Versandbedingungen:: Blue Ice