Recombinant Human IL-17C Protein

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£145.00

SKU:: RP02709
Zusätzliche Namen:: CX2|Cytokine CX2|IL-17C|IL-17CMGC126884|IL17C
Molekulargewicht:: 20-25 kDa
Reinheit:: ≥95%
Lagerbedingungen:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Immunogen:: His19-Val197
Formulierung:: Recombinant Human IL-17C Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (His19-Val197) of Human IL-17C (Accession #NP_037410.1) fused with a His tag at the C-terminus.
Spezies:: Human
Uniprot:: Q9P0M4
Synonyme:: CX2;cytokine CX2;IL-17C;interleukin-17C
Weitere Details:: Interleukin 17C (IL-17C) is a 15-20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. The six IL-17 cytokines (IL?17A?F) are encoded by separate genes but adopt a conserved cystine knot fold. IL?17C is Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G.