RP02679
Recombinant Human IL-17RB Protein
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£395.00
- SKU:
- RP02679
- Zusätzliche Namen:
- Evi27|IL-17 receptor B|IL-17 RH1|IL-17ER|IL-17RB|IL17RB
- Molekulargewicht:
- 45-60 kDa
- Reinheit:
- ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Immunogen:
- Arg18-Per292
- Formulierung:
- Recombinant Human IL-17RB Protein is expressed from Expi293 with His tag at the C-terminal.; It contains Arg18-Per292.
- Spezies:
- Human
- Uniprot:
- Q9NRM6-1
- Synonyme:
- CRL4;cytokine receptor CRL4;cytokine receptor-like 4;EVI27;IL-17 receptor B;IL-17 receptor homolog 1;IL-17B receptor;IL-17RB;IL-17Rh1;IL17BR;IL17RH1;interleukin 17 receptor homolog 1;interleukin-17 receptor B;interleukin-17B receptor
- Weitere Details:
- Among inflammatory mediators, a growing body of evidence emphasizes the contribution of the interleukin 17 (IL-17) cytokine family in malignant diseases. Besides IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. In mouse models, IL-17B signaling through IL-17RB directly promotes cancer cell survival, proliferation, and migration, and induces resistance to conventional chemotherapeutic agents.
- Versandbedingungen:
- Blue Ice