RP02589B
Biotinylated Recombinant Human LILRA3/ILT-6/CD85e Protein
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£657.00
- SKU:
- RP02589B
- Zusätzliche Namen:
- CD85e|HM31|HM43|ILT-6|ILT6|LILRA3|LIR-4HM43e3|LIR4
- Molekulargewicht:
- 60-70 kDa
- Reinheit:
- ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Immunogen:
- Gly24-Glu439
- Formulierung:
- Biotinylated Recombinant Human LILRA3/ILT-6/CD85e Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly24-Glu439) of Human LILRA3/ILT-6/CD85e (Accession #) fused with His tag and Avi Tag at the C-terminal.
- Spezies:
- Human
- Uniprot:
- Q8N6C8
- Synonyme:
- CD85 antigen-like family member E;CD85E;HM31;HM43;ILT-6;ILT6;immunoglobulin-like transcript 6;leucocyte Ig-like receptor A3;leukocyte immunoglobulin-like receptor 4;leukocyte immunoglobulin-like receptor subfamily A member 3;leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3;LIR-4;LIR4;monocyte inhibitory receptor HM43/HM31
- Weitere Details:
- Human LILRA3, also known as Leukocyte Ig-like receptor 4 (LIR-4), CD85 antigen-like family member E, Immunogobulin-like transcript 6 (ILT-6) and monocyte inhibitory receptor HM43/HM31,? is a 70 kD Ig superfamily member that belongs to the leukocyte receptor complex/cluster. Mature LILRA3 is 416 amino acids (aa) in length and contains four C2-type Ig-like domains . Unlike other LILR family members, LILRA3 is actively secreted.LILRA3 acts as soluble receptor for class I MHC antigens. LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.
- Versandbedingungen:
- Blue Ice