RP02478B
Biotinylated Recombinant Human PDGFR-beta/CD140b Protein
Größe
£657.00
- SKU:
- RP02478B
- Zusätzliche Namen:
- CD140B,IBGC4,IMF1,JTK12,KOGS,PDGFR,PDGFR-1,PDGFR1,PENTT,PDGF Receptor beta,PDGFRB,PDGFR beta
- Molekulargewicht:
- 78-115 kDa
- Reinheit:
- ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Immunogen:
- Leu33-Phe530
- Formulierung:
- Biotinylated Recombinant Human PDGF R beta Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Leu33-Phe530) of Human PDGF R beta fused with His tag and Avi tag at the C-terminal.
- Spezies:
- Human
- Uniprot:
- P09619
- Synonyme:
- Activated tyrosine kinase PDGFRB;Beta platelet-derived growth factor receptor;beta-type platelet-derived growth factor receptor;CD140 antigen-like family member B;CD140B;IBGC4;IMF1;JTK12;KOGS;NDEL1-PDGFRB;PDGF-R-beta;PDGFR;PDGFR-1;PDGFR-beta;PDGFR1;PENTT;platelet-derived growth factor receptor 1;platelet-derived growth factor receptor beta;platelet-derived growth factor receptor, beta polypeptide
- Weitere Details:
- PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Where as PDGF R alpha binds all three PDGF isoforms with high affinity, PDGF R beta binds PDGF-BB only with high-affinity. PDGF R plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites.
- Versandbedingungen:
- Blue Ice