RP02461B
Biotinylated Recombinant Human Notch 1 Protein
Größe
£657.00
- SKU:
- RP02461B
- Zusätzliche Namen:
- AOS5,AOVD1,TAN1,hN1,NOTCH1,Activated NOTCH1,notch 1, AOS5, AOVD1, TAN1, hN1, notch 1
- Molekulargewicht:
- 70-80 kDa
- Reinheit:
- ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 %
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Immunogen:
- Ala19-Gln526
- Formulierung:
- Biotinylated Recombinant Human Notch 1 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Ala19-Gln526) of Human Notch 1 fused with a His tag and Avi tag at the C-terminal.
- Spezies:
- Human
- Uniprot:
- P46531
- Synonyme:
- AOS5;AOVD1;hN1;neurogenic locus notch homolog protein 1;notch 1;Notch homolog 1, translocation-associated;TAN1;translocation-associated notch protein TAN-1
- Weitere Details:
- Human Notch-1 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes.Notch-1 functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.
- Versandbedingungen:
- Blue Ice