Recombinant Human Thioredoxin-2/MTRX/TXN2 Protein

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£145.00

SKU:: RP02177
Zusätzliche Namen:: COXPD29, MT-TRX, MTRX, TRX2, TXN,TXN2,MT-TRX,MTRX,TRX2,TXN
Molekulargewicht:: 13 kda
Reinheit:: ≥95%
Lagerbedingungen:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Immunogen:: Thr60-Gly166
Formulierung:: Recombinant Human Thioredoxin-2/MTRX/TXN2 Protein is produced by E.coli expression system. The target protein is expressed with sequence (Thr60-Gly166) of human TXN2 (Accession #Q99757) fused with a 6xHis tag at the N-terminus.
Spezies:: Human
Uniprot:: Q99757
Synonyme:: COXPD29;mitochondrial thioredoxin;MT-TRX;MTRX;Thioredoxin-2;thioredoxin, mitochondrial;TRX2;TXN
Weitere Details:: Thioredoxin-2 (TXN2) is a mitochondrial member of the thioredoxin family. Thioredoxin-2 is extensively expressed in adult and fetal tissues. Thioredoxin-2 contains an N-terminal 59 amino acid transit peptide, which is cleaved before translocating to mitochondria. Mitochondrial thioredoxin play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. Thioredoxin-2 could be involved in the resistance to anti-tumor agents and possesses a dithiol- reducing activity. In addition, Thioredoxin-2 is important at low oxidative stress conditions.