Recombinant Human/Mouse/Rat mature Activin A/INHBA Protein

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£163.00

SKU:: RP01782S
Zusätzliche Namen:: Activin A|EDF|FRP|INHBA
Molekulargewicht:: 15-20 kDa
Spezies-Reaktivität:: Human, Mouse, Rat
Reinheit:: ≥90%
Lagerbedingungen:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Immunogen:: Gly311-Ser426
Formulierung:: Recombinant Human/Mouse/Rat mature Activin A/INHBA Protein is produced by CHO cells expression system. The target protein is expressed with sequence (Gly311-Ser426) of Human/Mouse/Rat mature Activin A/INHBA (Accession #NP_002183.1) fused with No Tag.
Spezies:: Human, Mouse, Rat
Sequenz:: GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
Uniprot:: P08476
Synonyme:: activin beta-A chain;EDF;erythroid differentiation factor;erythroid differentiation protein;follicle-stimulating hormone-releasing protein;FRP;FSH-releasing protein;inhibin beta A chain;inhibin beta A subunit;inhibin, beta A (activin A, activin AB alpha polypeptide);Inhibin, beta-1
Weitere Details:: The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

Versandbedingungen:: Blue Ice