Recombinant Mouse CD52 Protein

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£133.00

SKU:: RP01565
Zusätzliche Namen:: CDW52,HE5,CD52,CAMPATH-1 antigen,CD52
Molekulargewicht:: 35-45 kDa
Reinheit:: ≥95%
Lagerbedingungen:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Immunogen:: Gly24-Ser47
Formulierung:: Recombinant Mouse CD52 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly24-Ser47) of mouse CD52 (Accession #NP_038734.1) fused with a hFc tag at the C-terminus.
Spezies:: Mouse
Sequenz:: GQATTAASGTNKNSTSTKKTPLKS
Uniprot:: Q64389
Synonyme:: AI463198;B7;B7-Ag;CAMPAT;CAMPATH-1;CAMPATH-1 antigen;CL;CLS1;lymphocyte differentiation antigen B7;MB7
Weitere Details:: CD52/CDW52 is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein. It has a mature peptide comprising only 12 amino acids and is abundantly expressed on human lymphocytes. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.