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RP01362

Recombinant Human IL-3 Protein

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£145.00

SKU:
RP01362
Zusätzliche Namen:
IL3,IL-3,MCGF,MULTI-CSF
Molekulargewicht:
20-35 kDa
Reinheit:
≥95%
Lagerbedingungen:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Hersteller:
Abclonal
Immunogen:
Ala20-Phe152
Formulierung:
Recombinant Human IL-3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala20-Phe152) of human interleukin-3/IL-3 (Accession #NP_000579.2) fused with a 6xHis tag at the C-terminus.
Spezies:
Human
Sequenz:
APMTQTTPLKTSWVNCSNMIDEIITHLKQPPLPLLDFNNLNGEDQDILMENNLRRPNLEAFNRAVKSLQNASAIESILKNLLPCLPLATAAPTRHPIHIKDGDWNEFRRKLTFYLKTLENAQAQQTTLSLAIF
Uniprot:
P08700
Synonyme:
colony-stimulating factor, multiple;hematopoietic growth factor;IL-3;interleukin-3;Mast cell growth factor;mast-cell growth factor;MCGF;MULTI-CSF;multilineage-colony-stimulating factor;multipotential colony-stimulating factor;P-cell stimulating factor;P-cell-stimulating factor
Weitere Details:
IL3 (interleukin 3), also known as IL-3, is a potent growth-promoting cytokine that belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells. IL3/IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation, and apoptosis. IL3/IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
Versandbedingungen:
Blue Ice