Recombinant Human CCL11/Eotaxin Protein

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£145.00

SKU:: RP00812
Zusätzliche Namen:: CCL11, SCYA11, Eotaxin, C-C motif chemokine 11,Small-inducible cytokine A11
Molekulargewicht:: 5-15 kDa
Reinheit:: ≥90%
Lagerbedingungen:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Immunogen:: Gly24-Pro97
Formulierung:: Recombinant Human CCL11/Eotaxin Protein is produced by E. coli expression system. The target protein is expressed with sequence (Gly24-Pro97) of human CCL11/Eotaxin (Accession #P51671).
Spezies:: Human
Uniprot:: P51671
Synonyme:: C-C motif chemokine 11;chemokine (C-C motif) ligand 11;eosinophil chemotactic protein;eotaxin;eotaxin-1;SCYA11;small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin);Small-inducible cytokine A11
Weitere Details:: CCL11 is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of allergic inflammatory reactions. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for CCL11 include CCR2, CCR3 and CCR5. However, it has been found that CCL11 has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3.