RP00807
Recombinant Mouse IL-2 (C160S) Protein
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£133.00
- SKU:
- RP00807
- Zusätzliche Namen:
- Il2, Il-2,Interleukin-2, IL-2, T-cell growth factor, TCGF
- Molekulargewicht:
- 15-20 kDa
- Reinheit:
- ≥90%
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Immunogen:
- Ala21-Gln169
- Formulierung:
- Recombinant Mouse IL-2 (C160S) Protein is produced by E. coli cells expression system. The target protein is expressed with sequence (Ala21-Gln169) of Mouse IL-2 (Accession # NP_032392.1) fused with No tag.
- Spezies:
- Mouse
- Uniprot:
- P04351
- Synonyme:
- IL;Il-2;interleukin-2;T-cell growth factor;TCGF
- Weitere Details:
- Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family which includes IL-4, IL-7, IL-9, IL-15 and IL-21. Each member of this family has a four alpha helix bundle. IL-2 signals through the IL-2receptor, a complex consisting of tree subunits, termed alpha, beta and gamma. The IL-2 R gamma is shared bycytokine receptors of all members of cytokine family. Mature mouse IL -2 shares 56% and 73% aa sequenceidentity with human and rat IL-2, respectively. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma D Delta T cells, Bcells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance andimmunity, primarily via its potent stimulatory activity for T cells.Thus, IL-2 may be a key cytokine in the naturalsuppression of autoimmunity.
- Versandbedingungen:
- Blue Ice