RP00634
Recombinant Human IL-31 Protein
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£431.00
- SKU:
- RP00634
- Zusätzliche Namen:
- IL-31|IL31|Interleukin-31
- Molekulargewicht:
- 20-25 kDa
- Reinheit:
- ≥ 95 % as determined by SDS-PAGE;≥ 95 %
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Immunogen:
- Ser24-Thr164
- Formulierung:
- Recombinant Human IL-31 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser24-Thr164) of Human IL-31 (Accession #Q6EBC2-1) fused with a N-His tag at the N-terminus.
- Spezies:
- Human
- Sequenz:
- SHTLPVRLLRPSDDVQKIVEELQSLSKMLLKDVEEEKGVLVSQNYTLPCLSPDAQPPNNIHSPAIRAYLKTIRQLDNKSVIDEIIEHLDKLIFQDAPETNISVPTDTHECKRFILTISQQFSECMDLALKSLTSGAQQATT
- Uniprot:
- Q6EBC2-1
- Synonyme:
- IL-31;interleukin-31
- Weitere Details:
- Many autoimmune skin diseases, such as bullous pemphigoid (BP), psoriasis and certain types of chronic urticaria, are associated with intensive pruritus. While histamine and neuropeptides have previously been ascribed to play a role in itch that accompanies these diseases, recent evidence suggests that the pruritogenic cytokine interleukin (IL)-31 is a major driver of pruritic responses. IL-31 was originally shown to be produced by activated helper T cells, particularly Th2 cells, mast cells, macrophages and dendritic cells.
- Versandbedingungen:
- Blue Ice