RP00621B
Biotinylated Recombinant Human ALCAM/CD166 Protein
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£657.00
- SKU:
- RP00621B
- Zusätzliche Namen:
- ALCAM|CD166|CD6L|KG-CAM|MEMD
- Molekulargewicht:
- 72-80 kDa
- Reinheit:
- ≥ 95 % as determined by SDS-PAGE;≥ 95 %
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Immunogen:
- Trp28-Ala526
- Formulierung:
- Biotinylated Recombinant Human ALCAM/CD166 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Trp28-Ala526) of Human ALCAM/CD166 (Accession #Q13740-1) fused with a C-His&Avi tag at the C-terminus.
- Spezies:
- Human
- Sequenz:
- WYTVNSAYGDTIIIPCRLDVPQNLMFGKWKYEKPDGSPVFIAFRSSTKKSVQYDDVPEYKDRLNLSENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCTAENQLERTVNSLNVSAISIPEHDEADEISDENREKVNDQA
- Uniprot:
- Q13740-1
- Synonyme:
- Activated leukocyte cell adhesion molecule;CD166;CD166 antigen;MEMD
- Weitere Details:
- Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM.
- Versandbedingungen:
- Blue Ice