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RP00620B

Biotinylated Recombinant Human ALCAM/CD166 Protein (Primary Amine Labeling)

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£657.00

SKU:
RP00620B
Zusätzliche Namen:
ALCAM|CD166|CD6L|KG-CAM|MEMD
Molekulargewicht:
70-80 kDa
Reinheit:
≥95%
Lagerbedingungen:
-20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Hersteller:
Abclonal
Immunogen:
Trp28-Ala526
Formulierung:
Biotinylated Recombinant Human ALCAM/CD166 Protein (Primary Amine Labeling) is produced by HEK293 cells expression system. The target protein is expressed with sequence (Trp28-Ala526) of Human ALCAM/CD166 (Primary Amine Labeling) (Accession #Q13740-1) fused with a C-His tag at the C-terminus.
Spezies:
Human
Sequenz:
WYTVNSAYGDTIIIPCRLDVPQNLMFGKWKYEKPDGSPVFIAFRSSTKKSVQYDDVPEYKDRLNLSENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCTAENQLERTVNSLNVSAISIPEHDEADEISDENREKVNDQA
Uniprot:
Q13740-1
Synonyme:
Activated leukocyte cell adhesion molecule;CD166;CD166 antigen;MEMD
Weitere Details:
Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM.
Versandbedingungen:
Blue Ice