Recombinant Human SIRP-gamma/CD172g Protein

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£145.00

SKU:: RP00614
Zusätzliche Namen:: SIRPG,CD172g,SIRP-B2,SIRPB2,SIRPgamma,bA77C3.1
Molekulargewicht:: 70-80 kDa
Reinheit:: ≥95%
Lagerbedingungen:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Immunogen:: Glu29-Pro360
Formulierung:: Recombinant Human SIRP-gamma/CD172g Protein is produced by Human cells expression system. The target protein is expressed with sequence (Glu29-Pro360) of human SIRP-gamma/CD172g (Accession #Q9P1W8) fused with an Fc tag at the C-terminus.
Spezies:: Human
Sequenz:: EEELQMIQPEKLLLVTVGKTATLHCTVTSLLPVGPVLWFRGVGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRISSITPADVGTYYCVKFRKGSPENVEFKSGPGTEMALGAKPSAPVVLGPAARTTPEHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPTGQSVAYSIRSTARVVLDPWDVRSQVICEVAHVTLQGDPLRGTANLSEAIRVPPTLEVTQQPMRVGNQVNVTCQVRKFYPQSLQLTWSENGNVCQRETASTLTENKDGTYNWTSWFLVNISDQRDDVVLTCQVKHDGQLAVSKRLALEVTVHQKDQSSDATP
Uniprot:: Q9P1W8
Synonyme:: bA77C3.1;CD172 antigen-like family member B;CD172g;CD172g antigen;signal-regulatory protein beta-2;signal-regulatory protein gamma;SIRP beta 2;SIRP-B2;SIRP-gamma;SIRPB2;SIRPgamma
Weitere Details:: Signal-Regulatory Protein Gamma (SIRPG) is a member of the signal-regulatory protein (SIRP) family and alsobelongs to the immunoglobulin superfamily. SIRPG is detected in the liver, and at very low levels in the brain,heart, lung, pancreas, kidney, placenta, and skeletal muscle. SIRPG is an immunoglobulin-like cell surfacereceptor. On binding with CD47, SIRPG mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.SIRPG as receptor-type transmembrane glycoproteins is involved in the negative regulation of receptortyrosine kinase-coupled signaling processes.

Versandbedingungen:: Blue Ice