RP00157
Recombinant Human Carbonic anhydrase 12 Protein
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£258.00
- SKU:
- RP00157
- Zusätzliche Namen:
- CA12,CA-XII,CAXII,HsT18816,T18816
- Molekulargewicht:
- 35-40 kDa
- Reinheit:
- ≥90%
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Immunogen:
- Ala25-Gln291
- Formulierung:
- Recombinant Human Carbonic anhydrase 12 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ala25-Gln291) of human Carbonic Anhydrase XII/CA12 (Accession #NP_001209.1) fused with a 6xHis tag at the C-terminus.
- Spezies:
- Human
- Sequenz:
- APVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQ
- Uniprot:
- O43570
- Synonyme:
- CA-XII;carbonate dehydratase XII;carbonic anhydrase 12;carbonic anhydrase XII;carbonic dehydratase;CAXII;HsT18816;T18816;tumor antigen HOM-RCC-3.1.3
- Weitere Details:
- Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA12, also known as Car12 and carbonic anhydrase XII, is a type I membrane enzyme that is highly expressed in normal tissues, such as colon, kidney, prostate, intestine and activated lymphocytes and moderately expressed in pancreas, ovary, and testis. It has been found to be overexpressed in 10% of clear cell renal carcinomas.
- Versandbedingungen:
- Blue Ice