RP00118
Recombinant Human MIC-B Protein
Größe
£181.00
- SKU:
- RP00118
- Zusätzliche Namen:
- MICB,PERB11.2
- Molekulargewicht:
- 75-100 kDa
- Reinheit:
- ≥ 95 % as determined by SDS-PAGE;≥95 %
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Immunogen:
- Ala23-Gly298
- Formulierung:
- Recombinant Human MIC-B Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ala23-Gly298) of human MICB (Accession #NP_005922.2) fused with an Fc, 6xHis tag at the C-terminus.
- Spezies:
- Human
- Sequenz:
- AEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSG
- Uniprot:
- Q29980
- Synonyme:
- MHC class I antigen-related protein B;MHC class I chain-related protein B;MHC class I mic-B antigen;MHC class I polypeptide-related sequence B;MHC class I-like molecule PERB11.2-IMX;PERB11.2;stress inducible class I homolog
- Weitere Details:
- This protein is a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice