Recombinant Human Tyrosine-protein kinase receptor UFO/Axl Protein

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£164.05

War £193.00

SKU:: RP00087
Zusätzliche Namen:: AXL,ARK,JTK11,Tyro7,UFO
Molekulargewicht:: 70-80 kDa
Reinheit:: ≥95%
Lagerbedingungen:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Immunogen:: Glu33-Pro449
Formulierung:: Recombinant Human Tyrosine-protein kinase receptor UFO/Axl Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Glu33-Pro449) of human Axl (Accession #NP_001690.2) fused with a 6xHis tag at the C-terminus.
Spezies:: Human
Sequenz:: EESPFVGNPGNITGARGLTGTLRCQLQVQGEPPEVHWLRDGQILELADSTQTQVPLGEDEQDDWIVVSQLRITSLQLSDTGQYQCLVFLGHQTFVSQPGYVGLEGLPYFLEEPEDRTVAANTPFNLSCQAQGPPEPVDLLWLQDAVPLATAPGHGPQRSLHVPGLNKTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHCTLQAVLSDDGMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISATRNGSQAFVHWQEPRAPLQGTLLGYRLAYQGQDTPEVLMDIGLRQEVTLELQGDGSVSNLTVCVAAYTAAGDGPWSLPVPLEAWRPGQAQPVHQLVKEPSTPAFSWP
Uniprot:: P30530
Synonyme:: ARK;AXL oncogene;AXL transforming sequence/gene;JTK11;Tyro7;tyrosine-protein kinase receptor UFO;UFO
Weitere Details:: The protein is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.

Versandbedingungen:: Blue Ice