RP00051
Recombinant Human FKBP1A/FKBP12 Protein
Größe
£115.00
- SKU:
- RP00051
- Zusätzliche Namen:
- FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE,FKBP1A,FKBP-1A,FKBP1,FKBP12,PKC12,PKCI2,PPIASE
- Molekulargewicht:
- 14 kDa
- Reinheit:
- ≥90%
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Immunogen:
- Met1-Glu108
- Formulierung:
- Recombinant Human FKBP1A/FKBP12 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Glu108) of human FKBP12 (Accession #NP_000792.1).
- Spezies:
- Human
- Sequenz:
- MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE
- Uniprot:
- P62942
- Synonyme:
- 12 kDa FK506-binding protein;12 kDa FKBP;calstabin-1;FK506 binding protein 1A, 12kDa;FK506 binding protein12;FK506-binding protein 1;FK506-binding protein 12;FK506-binding protein 1A;FK506-binding protein, T-cell, 12-kD;FKBP-12;FKBP-1A;FKBP1;FKBP12;FKBP12-Exip3;immunophilin FKBP12;peptidyl-prolyl cis-trans isomerase FKBP1A;PKC12;PKCI2;PPIASE;PPIase FKBP1A;protein kinase C inhibitor 2;rotamase
- Weitere Details:
- The protein is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor.
- Versandbedingungen:
- Blue Ice