RP00038
Recombinant Human IL-16 Protein
Größe
£163.00
- SKU:
- RP00038
- Zusätzliche Namen:
- IL16,LCF,NIL16,PRIL16,prIL-16
- Molekulargewicht:
- 20 kDa
- Reinheit:
- ≥95%
- Lagerbedingungen:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Immunogen:
- Pro2-Ser130
- Formulierung:
- Recombinant Human IL-16 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Pro2-Ser130) of human IL-16 (Accession #NP_757366.2) fused with a 6xHis tag at the C-terminus.
- Spezies:
- Human
- Sequenz:
- PDLNSSTDSAASASAASDVSVESTAEATVCTVTLEKMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQSKETTAAGDS
- Uniprot:
- Q14005
- Synonyme:
- LCF;lymphocyte chemoattractant factor;neuronal interleukin 16;NIL16;prIL-16;PRIL16;pro-interleukin-16;prointerleukin 16
- Weitere Details:
- The protein is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The biological activities ascribed to IL-16 are reported to be dependent on the cell surface expression of CD4, suggesting that IL-16 is a CD4 ligand. Besides its chemotactic properties, IL-16 has also been shown to suppress HIV-1 replication in vitro. Recombinant E. coli-derived IL-16 produced at is present mostly as a monomer, exhibits chemotactic activity for lymphocytes at high concentrations, lacks chemotactic activites for monocytes, and binds the extracellular domain of CD4 with low affinity.
- Versandbedingungen:
- Blue Ice