Rabbit anti-Human IL-18 monoclonal antibody

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£372.30

War £438.00

SKU:: RMK0591
Zusätzliche Namen:: IGIF|IL-18|IL-1g|IL1F4
Anwendung:: ELISA
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Abclonal
Reaktivitäten:: Human
Immunogen:: Recombinant Human IL-18 protein
Formulierung:: Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.3.
Spezies:: Human
Uniprot:: Q14116
Synonyme:: iboctadekin;IFN-gamma-inducing factor;IGIF;IL-1 gamma;IL-18;IL-1g;IL1F4;Interferon gamma-inducing factor;interleukin 18 (interferon-gamma-inducing factor);interleukin-1 gamma;interleukin-18
Weitere Details:: The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.