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RMK0513

Rabbit anti-Human Interleukin 18 Binding Protein/IL-18BP monoclonal antibody

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£372.30

War £438.00

SKU:
RMK0513
Zusätzliche Namen:
FVH|IL18BPa
Anwendung:
ELISA
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C
Hersteller:
Abclonal
Immunogen:
Recombinant Human Interleukin 18 Binding Protein/IL-18BP protein
Formulierung:
Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.3.
Spezies:
Human
Uniprot:
O95998
Synonyme:
FVH;IL18BPa;interleukin-18-binding protein;MC51L-53L-54L homolog gene product;tadekinig-alfa
Weitere Details:
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Versandbedingungen:
Dry Ice