Rabbit anti-Mouse IL-10 monoclonal antibody

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£372.30

War £438.00

SKU:: RMK0423
Zusätzliche Namen:: CSIF|If2a|Il-10
Spezies-Reaktivität:: Mouse
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Immunogen:: Recombinant Mouse IL-10 Protein
Formulierung:: Supplied as a 0.2um filtered solution in PBS with 0.05% Proclin300, PH 7.4.
Spezies:: Mouse
Uniprot:: P18893
Synonyme:: CSIF;cytokine synthesis inhibitory factor;GVHDS;If2a;IL-;IL-10;IL10A;interferon 2a;interleukin-10;T-cell growth inhibitory factor;TGIF
Weitere Details:: Interleukin-10 (IL-10), also known as cytokine synthesis inhibitory factor (CSIF), is the charter member of the IL-10 alpha -helical cytokine family that also includes IL-19, IL-20, IL-22, IL-24, and IL-26/AK155 (1-3). IL-10 is secreted by many activated hematopoietic cell types as well as hepatic stellate cells, keratinocytes, and placental cytotrophoblasts. Whereas human IL-10 is active on mouse cells, mouse IL-10 does not act on human cells (4, 5). Mature mouse IL-10 shares 85% amino acid sequence identity with rat IL-10 and 70-77% with bovine, canine, equine, feline, human, ovine, and porcine IL-10. It contains two intrachain disulfide bridges and is expressed as a 36 kDa noncovalently-associated homodimer