Rabbit anti-Human CD163 monoclonal antibody(CAP)

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£372.30

War £438.00

SKU:: RMK0324
Zusätzliche Namen:: M130|MM130|SCARI1
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Abclonal
Immunogen:: Recombinant human CD163 Protein
Formulierung:: Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, PH 7.4.
Spezies:: Human
Uniprot:: Q86VB7
Synonyme:: hemoglobin scavenger receptor;M130;macrophage-associated antigen;MM130;SCARI1;scavenger receptor cysteine-rich type 1 protein M130
Weitere Details:: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.