Rabbit anti-Human Fas Ligand/TNFSF6 monoclonal antibody

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£372.30

War £438.00

SKU:: RMK0035
Zusätzliche Namen:: ALPS1B|APT1LG1|APTL|CD178|CD95-L|CD95L|FASL|TNFSF6|TNLG1A
Anwendung:: ELISA
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Abclonal
Immunogen:: Recombinant fusion protein containing a sequence corresponding to amino acids 134-281 of human Fas Ligand/CD178 (NP_000630.1).
Formulierung:: Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300,PH 7.4.
Spezies:: Human
Uniprot:: P48023
Synonyme:: ALPS1B;apoptosis (APO-1) antigen ligand 1;apoptosis antigen ligand;APT1LG1;APTL;CD178;CD95 ligand;CD95-L;CD95L;fas antigen ligand;Fas ligand (TNF superfamily, member 6);FASL;mutant tumor necrosis factor family member 6;TNFSF6;TNLG1A;tumor necrosis factor ligand 1A;tumor necrosis factor ligand superfamily member 6
Weitere Details:: This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.